The Optovibronex Device

The Science

Vibrational OCT combines the techniques of OCT and Vibrational analysis to generate both an image and information about mechanical properties of the sample under test. Sound waves are used to generate vibrations.


  • OptoScope 2.0™ is a next-generation material characterization device
  • Scans the area of interest in less than 10 minutes from software setup to scan completion
  • Sound and light is not felt by patient
  • The non-invasive combination of infrared light and transverse vibrational waves create a detailed 2D and 3D image and preserves the area or sample being scanned.
  • Measures tissue/material elasticity and viscosity non-invasively. No other characterization technique is known to track material changes in cellular components of human tissue or determine likelihood of failure in non-organic materials.
  • OptoScope 2.0™ device can be calibrated against a gold standard

Current Focus

OptoVibronex is currently focused on OptoScope 2.0™ applications in Dermatology, particularly Aesthetic Dermatology. There are multiple products and procedures available to patients looking for aesthetic changes to their features. OptoScope 2.0™ can measure collagen and other material changes over real and accelerated time. These measurements can assist product companies with their development efforts and commercial claims, as well as assist practitioners develop and modify treatment programs.

OptoVibronex is also addressing recent interest from the Wound Care area. Look for more news on OptoScope 2.0™ applications in this area in the coming months!

Meet Dr. Fred Silver

Developer of OptoScope 2.0™

Fred Silver, Chief Technical Officer at OptoVibronex, is Professor of Pathology at Robert Wood Johnson Medical School, Rutgers University, for 35 years. He holds over 30 patents on materials, tissues and their mechanical characterization. He received his B.S. in Chemical Engineering from Northeastern University and completed his Ph.D. in Polymer Science and Engineering with a Minor in Biology from MIT. Dr. Silver has published over 200 research papers, books and abstracts dealing with biological materials – over 25 within the last 2 years. He has been asked to speak internationally at dermatology and material science conferences. Over the years, Fred has also purchased and revitalized a number of small businesses.

For an archive of Dr. Fred Silver’s publications, click here.

Potential Uses

Dermatology & Aesthetic Dermatology

To date, OptoVibronex OptoScope 2.0™ technology has been most appealing to Dermatologists and Aesthetic Dermatologists. Our technology has several potential applications including characterization of tissues and implants, collagen deposition and/or collagen increases over time, measurement of sub-epithelial skin regeneration and evaluation of the efficacy of topical agents.

Cancer and Wound Healing

OptoScope 2.0™ can achieve vibrational virtual biopsies for Moh’s surgical procedures and help with identification of changes in tissue stiffness for cancerous lesions, non-invasive determination of margins for skin lesions, identification of lesion types, characterization of tissue in breast tissue biopsies and analysis of dermal wound healing, among many other potential applications.

Other Applications

OptoScope 2.0™ has potential applications in many other areas. These include medical applications like identification of corneal and scleral pathology in Ophthalmology, quantitative assessment of carotid artery behavior and identification of injection site blood vessels.

The technology also has uses outside of medicine in Industrial areas such as mechanical testing of different substances and in Arts & Sciences in areas such as age confirmation of artwork or other dated materials.

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